Yeah, but what fun would that be? And yes they kill well, but not nearly as decisively. I have to add that I have been present when the .44 has been used on really large animals and it's not that impressive unless CNS is hit.
I used a 44 mag Ruger Redhawk in Australia in 2009. Due to Australia laws I could not import my revolvers but I could use the guide's revolver. It worked and I killed 1 Trophy Bull, 3 Management Bulls, 1 cow, and a hog. The 44 mag worked but resulted in 100-400 yards of tracking. I would have much rather used a 475 or 500.