Tough call to pick just one.
My S&W 629 is the best offhand, point and shoot gun I own. I also like my Redhawk in 44 magnum, with or without a scope. That being said I am hunting this season with a scoped, X frame 460 S&W.
"Therefore go and make disciples of all nations,... "
Handgun hunter since 1979 - haven't used a rifle since!
HHI member #992, NRA, SCI.